Blog
Gender Differences in NO System
Many studies have shown that nitric oxide (NO) production is higher in the systemic vasculature of females than males and is stimulated during pregnancy, a high estrogen state. The present study was performed in rats to determine whether females had a greater...
NO A little molecule’s remarkable feat prolonging life
Nitric oxide, the versatile gas that helps increase blood fl ow, transmit nerve signals, andregulate immune function, appears to perform one more biological feat -- prolonging the life ofan organism and fortifying it against environmental stress, according to a new...
NO and Oxidative stress in Cardiovascular Aging
The long-standing free radical theory of aging, which attributes cellular pathology to the relentless accumulation of reactive oxygen species (ROS), remains attractive but controversial. Emerging insights into the molecular interactions between ROS and reactive...
Physical Activity and NO Availability in Elderly Athletes
Background—Aging is associated with increased cardiovascular risk and endothelial dysfunction. Since exercise can improve endothelium-dependent vasodilation, in the present study we tested whether long-term physical activity could prevent aging-related endothelial...
Implications in Elderly Diagnostics and Treatment
The nation’s aging population is growing rapidly. By 2030, the number of adults age 65 and older will nearly double to 70 million. Americans are living longer and older adults can now live for many years with multiple chronic illnesses but with a substantial cost to...
Fountain of Youth for Vascular Disease
Ponce de León was a 16th century Spanish explorer in search of the fountain of youth, a source of magical watercapable of reversing the aging process. Whether this tale existed at all, was a fleeting interest of King Ferdinand or a motivational tactic for his crew...
NO, Aging and Aerobic Exercise
Aging is associated with a decline in physiological function and exercise performance. These effects are mediated, at least in part, by an age-related decrease in the bioavailability of nitric oxide (NO), a ubiquitous gasotransmitter and regulator of myriad...
NO Pathway on Healthy Aging
We are living longer. Are we living healthier? As we age, cellular and molecular damage reshape our physiological responses towards environmental and endogenous stimuli. The free radical theory of aging has been proposed long before aging has been considered a...